October 6, 2022- Our review article is published on Frontiers in Immunology, reporting the targeting of tumor microenvironment by innate T cells. Congratulations to all the authors, in particular to the co-first authors Yan-Ruide (Charlie) Li and Matthew Wilson! [Frontiers in Immunology PDF]
September 1, 2022- Our research article is published on Frontiers in Pharmacology, reporting that nanoformulation improves antitumor efficacy of MAOI immune checkpoint blockade therapy without causing aggression-related side effects. Congratulations to all the authors, in particular to the first author James Brown and the co-corresponding author Bo Li! [Frontiers in Pharmacology PDF]
August 16, 2022- Our research article is published on iScience, reporting the development of “off-the-shelf” third-party iNKT cells for improving bone marrow transplant safety. Congratulations to all the authors, in particular to the co-first authors Yan-Ruide (Charlie) Li and Sam Zeng! This publication is featured on UCLA News. [iScience PDF][UCLA News PDF]
July 7, 2022- Our research article is published on International Journal of Molecular Sciences, reporting the tumor-localized adminisatration of a-GalCel to recruit invariant natural killer T cells and enhance their antitumor activity against solid tumors. Congratulations to all the authors, in particular to the first author Yan-Ruide (Charlie) Li! [International Journal of Molecular Sciences PDF]
June 30, 2022- Our review article is published on International Journal of Molecular Sciences, reporting interleukin 15 (IL-15) in cell-based cancer immunotherapy. Congratulations to all the authors, in particular to the co-first authors Yang (Alice) Zhou and Husman Tiffany! [International Journal of Molecular Sciences PDF]
June 8, 2022- Our review article is published on Cancers, reporting human gamma-delta T (rdT) cell subsets and their clinical applications for cancer immunotherapy. Congratulations to all the authors, in particular to the first author Derek Lee! [Cancers PDF]
June 1, 2022- Our research article is published on Cancers, reporting the targeting of immunosuppressive tumor-associated macrophages (TAMs) using innate T cells for enhanced antitumor reactivity. Congratulations to all the authors, in particular to the first author Yan-Ruide (Charlie) Li! [Cancers PDF]
May 8, 2022- Our research article is published on Cells, reporting an ex vivo 3D tumor microenvironment-mimicry culture to study tumor-associated macrophage (TAM)-modulation of cancer immunotherapy. Congratulations to all the authors, in particular to the co-first authors Yan-Ruide (Charlie) Li and Yanqi (Darren) Yu! [Cells PDF]
May 1, 2022- Our review article is published on Cells, reporting the engineering of iPSCs for cancer immunotherapy. Congratulations to all the authors, in particular to the co-first authors Yang (Alice) Zhou, Miao (Eric) Li, and Kuangyi (Coin) Zhou! [Cancers PDF]
April 19, 2022- Dr. Lili Yang is featured on the anniversary issue of Cell Reports Medicine. Congratulations! [Cell Reports Medicine PDF]
March 31, 2022- Our research article is published on Cancers, reporting a new method for minimally invasive preclinical monitoring of the peritoneal cavity tumor microenvironment. Congratulations to all the authors, in particular to the first author Zach Dunn! [Cancers PDF]
March 14, 2022- Our review article is published on Frontiers in Immunology, reporting MAOI antidepressants as the next-generation immune checkpoint blockade (ICB) therapy. Congratulations to all the authors, in particular to the co-first authors James Brown and Bo Li! [Frontiers in Immunology PDF]
March 21, 2022- Our research article is published on Stem Cell Research & Therapy, reporting the development of off-the-shelf hematopoietic stem cell-engineered invariant natural killer T cells for COVID-19 therapeutic intervention. Congratulations to all the authors, in particular to the first-author Yan-Ruide (Charlie) Li! This publication is featured on UCLA Blog. [Stem Cell Research & Therapy PDF][UCLA Blog PDF]
December 10, 2021- Our review article is published on Cells, reporting the development of stem cell-derived immune cells for off-the-shelf cancer immunotherapies. Congratulations to all the authors, in particular to the co-first authors Yan-Ruide (Charlie) Li and Zach Dunn! [Cells PDF]
December 1, 2021- Our review article is published on Trends in Cancer, reporting the engineering of stem cells for cancer immunotherapy. Congratulations to all the authors, in particular to the first author Yan-Ruide (Charlie) Li!
November 16, 2021- Our research article is published on Cell Reports Medicine, reporting a step closer to making “off-the-shelf” immune cell therapy for cancer. Congratulations to all the authors, in particular to the co-first authors Yan-Ruide (Charlie) Li & Zhou (Alice) Yang! This publication is featured on multiple news media. [Cell Reports Medicine PDF][UCLA News PDF][BSCRC News PDF][JCCC News PDF][CIRM Blog PDF]
June 10, 2021- Our two research articles are published on Science Immunology and Nature Communications, reporting the identification of monoamine oxidase A (MAO-A) as an immune checkpoint restraining T cell antitumor immunity and modulating tumor-associated macrophage polarization, as well as the potential of repurposing MAO inhibitor (MAOI) antidepressants for cancer immunotherapy. Congratulations to all the authors, in particular to the first-authors Shirley Xi Wang and Ryan Yu-Chen Wang! This publication is featured on multiple news media. [Science Immunology PDF][Nature Communications PDF][Science Magazine News PDF][UCLA News PDF][CBS News PDF][NBC News PDF][Fierce Biotech News PDF][Drug Target Review News PDF]
October 18, 2019- Our research article is published on the Journal of Experimental Medicine, reporting creatine uptake regulation of CD8 T cell immunity. Congratulations to all the authors, in particular to the first-author Stefano Di Biase! This publication is featured on multiple news media. [JEM PDF][UCLA News][UC News][MedicalXpress][ScienceDaily][The Medical News][Technology Networks]
September 5, 2019- Our research article is published on Cell Stem Cell, reporting the development of an HSC-engineered iNKT cell therapy for cancer. Congratulations to all the authors, in particular to the co-first authors Yanni Zhu and Drake Smith! This publication is featured on multiple news media. [Cell Stem Cell PDF][CSC Highlight][UCLA News][Medical News Today][The Stem Cell Podcast]