Scalable generation of hematopoietic stem cell-engineered off-the-shelf mono-specific cytotoxic T cells targeting solid tumors

Scalable generation of hematopoietic stem cell-engineered off-the-shelf mono-specific cytotoxic T cells targeting solid tumorsZhu Y*, Yu J*, Kim YJ, Tian Y, Li Z, Chen Y, Lyu Z, Zhu E, Zhao AS, Ma N, Zhang C, Kramer A, Wilson M, Hon R, Wang Y-C, Lin S, Shen X, Hahn Z, Zhang Y, Wang A, Li Y-R# and Yang L#. (*Co-first authors; #Co-corresponding authors). Adoptive Scalable generation of hematopoietic stem cell-engineered off-the-shelf mono-specific cytotoxic T cells targeting solid tumors. Cell Rep Med. 2026 Aug 19:102998. doi: 10.1016/j.xcrm.2026.102998. Online ahead of print. [Cell Reports Medicine  Main Article PDF  Supplemental Information PDF]