Research Highlights

Our research centers on deciphering the molecular mechanisms controlling antitumor immunity, and exploiting knowledge to device new gene- and cell-based cancer immunotherapies.

We have two active research directions:

  1. Studying the molecular control of antitumor immunity.
  2. Developing new gene- and cell-based immunotherapies for treating cancer.

Featured Publications

Smith DJ, Liu S, Ji S, Li B, McLaughlin J, Cheng D, Witte ON, and Yang L. Genetic Engineering of hematopoietic stem cells to generate invariant natural killer T cells. Proc. Natl. Acad. Sci. USA. 2015, 112(5):1523-28. [PDF][Link]
Li B*, Wang X*, Choi I, Liu S, Pham A, Moon H, Rao DS, Boldin MP, and Yang L. (Co-first authors). miR-146a modulates autoreactive CD4 T cell Th17 differentiation and regulates T cell-mediated autoimmunity. J Clin Invest. 2017, 127(10):3702-3716. [PDF][Link]

Featured News

May 11, 2017

Dr. Lili Yang receives the Outstanding New Investigator Award from the American Society of Gene & Cell Therapy (ASGCT). [PDF][Link]

March 23, 2016

Dr. Lili Yang receives a $7.6M CIRM 2.0 Partnering Opportunity for Translational Research Projects Award to translate a new stem cell-based immunotherapy