June 12, 2021
We are currently recruiting PhD students (2 openings) and postdoctoral researchers (3 openings). Welcome to apply! [PhD Openings][Postdoc Openings]...... Read More
Our research centers on deciphering the molecular mechanisms controlling antitumor immunity, and exploiting knowledge to device new gene- and cell-based cancer immunotherapies.
We have two active research directions:
Wang Y-C, Wang X, Yu J, Ma F, Li Z, Zhou Y, Zeng S, Ma X, Li Y-R, Neal A, Huang J, To A, Clarke N, Memarzadeh S, Pellegrini M, and Yang L. Targeting monoamine oxidase A-regulated tumor-associated macrophage polarization for cancer immunotherapy. Nat. Commun. 2021, 12:3530 (epub on June 10) [Nature Communications PDF][UCLA News PDF][CBS News PDF][NBC News PDF][Fierce Biotech News PDF][Drug Target Review News PDF]
Wang X, Li B, Kim Y, Wang Y, Li Z, Yu J, Zeng S, Ma X, Choi I, Di Biase S, Smith DJ, Zhou Y, Li Y, Ma F, Huang J, Clarke N, To A, Gong L, Pham A, Moon H, Pellegrini M, and Yang L. Targeting monoamine oxidase A for T cell-based cancer immunotherapy. Sci. Immunol. 2021, 6:eabh2383 (epub ahead of print). [Science Immunology PDF][Science Magazine News PDF][UCLA News PDF][CBS News PDF][NBC News PDF][Fierce Biotech News PDF][Drug Target Review News PDF]
Zhu Y.*, Smith DJ*, Zhou Y, Li YR, Yu J, Lee D, Wang Y-C, Di Biase S, Wang Xi, Hardoy C, Ku J, Tsao T, Lin LJ, Pham AT, Moon H, McLaughlin J, Cheng D, Hollis RP, Campo-Fernandez B, Urbinati F, Wei L, Pang L, Rezek V, Berent-Maoz B, Macabali MH, Gjertson D, Wang X, Galic Z, Kitchen SG, An DS, Hu-Lieskovan S, Kaplan-Lefko PJ, De Oliveira SN, Seet CS, Larson SM, Forman SJ, Heath JR, Zack JA, Crooks GM, Radu GR, Ribas A, Kohn DB, Witte ON, and Yang L. (Co-first authors). Development of hematopoietic stem cell-engineered invariant natural killer T cell therapy for cancer. Cell Stem Cell. 2019, 25(4):542-557. Epub 2019 Sept 5. [Link][PDF][CSC Highlight]
We are currently recruiting PhD students (2 openings) and postdoctoral researchers (3 openings). Welcome to apply! [PhD Openings][Postdoc Openings]...... Read More
Our two papers are published on Science Immunology and Nature Communications, reporting the identification of monoamine oxidase A (MAO-A) as...... Read More
Dr. Lili Yang receives a $5.9 million CIRM Partnering Opportunity for Translational Research Projects Award to translate a new stem...... Read More
Our off-the-shelf cell therapy technology is licensed by a Biotech startup, Appia Bio, for commercial development. The company launches with...... Read More